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Overproduction of Recombinant Human VEGF (Vascular Endothelial Growth Factor) in Chinese Hamster Ovary Cells
1Graduate School of Biotechnology, Kyung Hee University, Yongin 449-701, Korea, 2PanGen Biotech Inc., 5F NKBio Bldg., Seongnam 462-807, Korea, 3School of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea
J. Microbiol. Biotechnol. 2008; 18(1): 183-188
Published January 28, 2008
Copyright © The Korean Society for Microbiology and Biotechnology.
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J. Microbiol. Biotechnol. 2008; 18(1): 183-188
Published online January 28, 2008
Copyright © The Korean Society for Microbiology and Biotechnology.
Overproduction of Recombinant Human VEGF (Vascular Endothelial Growth Factor) in Chinese Hamster Ovary Cells
Lee, Seong-Baek 2, 3, Jeong Soo Park 2, Seunghee Lee 2, Junho Park 2, Sungryul Yu 1, Heechan Kim 1, Dongjun Kim 2, Tae Ho Byun 2, Kwanghee Baek 1, Young-Joon Ahn 3 and Jaeseung Yoon 2*
1Graduate School of Biotechnology, Kyung Hee University, Yongin 449-701, Korea, 2PanGen Biotech Inc., 5F NKBio Bldg., Seongnam 462-807, Korea, 3School of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea
Abstract
Vascular endothelial growth factors (VEGFs) are a family of proteins that mediate angiogenesis.
Keywords: recombinant protein expression, stable cell line, bioreactor process, VEGF, Chinese hamster ovary (CHO) cell