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J. Microbiol. Biotechnol. 2004; 14(1): 202-204

Published online February 28, 2004

Copyright © The Korean Society for Microbiology and Biotechnology.

Inhibitory Effect of Ginseng Polysaccharides on Rotavirus Infection

Bae Eun Ah , Ji Eun Shin , Sung Hwan Park and Dong Hyun Kim *

College of Pharmacy Kyung Hee University Seoul 130-701 Korea

Abstract

Polysaccharides and saponins were isolated from the root of Panax ginseng C.A. Meyer (Family Araliaceae), treated at various temperatures, and their inhibitory effects on rotavirus were investigated. As the temperature of processing increased, the molecular weight of the polysaccharides decreased, but the yields of water extracted increased. These polysaccharides inhibited rotavirus infection in MA104 cells, but there were no significant differences in rotavirus infection-inhibitory potency. However, ginseng saponins did not exhibit rotavirus infection-inhibitory activity.

Keywords: Panaxginseng,polysaccharide,ginsenoside,rotavirus