Fig. 7.

Fig. 7. ARO inhibits NLRP3 activation in experimental COPD mice. (A) The expression of NLRP3, ASC, and caspase-1 was analyzed using western blotting. Quantitative analysis of (B) NLRP3, (C) ASC, and (D) caspase-1 was performed using ImageJ software. Data are expressed as the mean ± SD (^#p < 0.05 for comparison with normal control; *p < 0.05 for comparison with COPD group). NC: normal control mice; COPD: cigarette smoke exposed/LPS-administered mice; ROF: 5 mg/kg ROF-treated COPD mice; ARO 5: 5 mg/kg ARO-treated COPD mice; and ARO 10: 10 mg/kg ARO-treated COPD mice.

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