Fig. 5.

Fig. 5. Effect of HPH on mast cell infiltration, IgE level, and macrophage level in the dorsal skin tissues of DNCB-sensitized BALB/c mice. After autopsy, dorsal skin tissue samples were obtained from individual mice from each group. (A and B) Dorsal skin tissue sections were stained with TB and anti-F4/80 antibodies. (C) Mast cell number. (D Serum IgE level. (E) Optical density of F40/80. The graphs show mean values. RNA was extracted from the dermal skin tissue of DNCB-induced BALB/c mice. (F) TARC, (G) RANTES, (H) and IL-4 mRNA expression levels were analyzed using qRT-PCR. Data are expressed as the mean ± S.D. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared with the control group. ^##p < 0.01, ^###p < 0.001, ^####p < 0.0001 compared with the normal group.

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