Journal of Microbiology and Biotechnology

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Table. 1.

Table. 1. Table 1

List of genes associated with the pathogenicity of C. auris.

Gene name	Description	Infection method	Virulence	Reference
HOG1	MAP kinase activity	Systemic infection	Strongly attenuated	[65]
PMR1	Involved in cell wall mannosylation	Systemic infection	Weakly attenuated	[66]
VAN1	Involved in cell wall mannosylation	Systemic infection	Weakly attenuated	[66]
DINOR	Modulating genome integrity, cell filamentation	Systemic infection	Strongly attenuated	[28]
BCY1	Protein kinase A regulatory subunit	Systemic infection	Weakly attenuated	[64]
ELM1	Involved in the regulation of cell morphology	Systemic infection	Strongly attenuated	[30]
PDE2	Involved negative regulation of cAMP-mediated RAS signaling	Systemic infection	Moderately attenuated	[63]
SAPA3	Primary aspartic-type endopeptidase	Systemic infection	Moderately attenuated	[67]
SCF1	Adhesin specifically required for adhesion in C. auris	Systemic and skin infection	Strongly attenuated	[68]

J. Microbiol. Biotechnol. 2024;34:1365~1375 https://doi.org/10.4014/jmb.2404.04040

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