Fig. 3.

Fig. 3. In vitro characterization of K15P38 variants. (A) Representative plaque images for Large and Small viruses. BHK-21 cells were infected with either virus, and images were captured 80 hours post-infection. (B) The diameter of thirty individual plaques from each virus type was measured in millimeters. (C, D) BHK-21 cells were infected with either the Large or Small virus at an MOI of 0.01. Viral titer (C) and the number of adherent cells (D) were assessed to examine the growth kinetics and cytotoxicity, respectively. Data represent mean ± SD values pooled from two independent experiments in duplicate wells (n = 4). *p < 0.05, ****p < 0.0001.

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