Fig. 2. Gene mutations and amino acid substitutions of the small plaque-forming variant.
(A) Location of four mutations on the viral genome. Mutations are indicated with black arrowheads at specific position numbers. Position numbers are counted based only on the open reading frame (ORF), excluding the untranslated regions. (B) Positions of amino acids on the translated polyprotein corresponding to the genetic mutations. Locations where substitutions occurred are highlighted in bold, with the substituted amino acids shown. nt: nucleotide, aa: amino acid.