Fig. 3. Effect of HDB7040 on the body weight change and food intake of OVX rats.
SD female rats underwent OVX surgery and were orally administered with HDB7040 for eight weeks. (A) Body weight change and (B) food intake were measured once and twice a week, and (C) weight gain was calculated by subtracting initial body weight from final body weight. Data are presented as the mean ± SD (n = 8). ##, p < 0.01; ###, p < 0.001, compared to the Sham group; *, p < 0.05; **, p < 0.01; ***, p < 0.001, compared to the OVX group.