Fig. 2. Regulatory effect of HDB7040 on ER mRNA expression.
(A) Expression of ESR1, (B) ESR2, and (C) changes in ESR2 expression by ICI pretreatment in HDB7040-treated MCF-7 cells expressed as a ratio to the internal standard (18S rRNA). Data are presented as the mean ± SEM (n = 3). **, p < 0.01; ***, p < 0.01, compared to the control; #, p < 0.05, compared to the non-ICI-treated group.