Fig. 1.

Fig. 1. The experimental scheme of this study. A mixture of antibiotics, containing ampicillin, metronidazole, neomycin and vancomycin, was treated to 6 week-old female BALB/c mice via drinking water for 1 week. Then, 200 μl of fermented milk contained 2 × 10⁵ CFUs of L. rhamnosus SNUG50430 was administered to mice once daily by oral gavage for 1 week. Colon samples were homogenized and the supernatant was collected after centrifugation at 15,000 ×g for 10 min at 4°C. Cytokine levels in the supernatant were measured. The PBS-antibiotics (PBS+Abx)-treated, the fermented milk without L. rhamnosus SNUG50430-antibiotics (FM+Abx)–treated, and the fermented milk with L. rhamnosus SNUG50430-antibiotics (FM+LR+Abx) group, were designed as each experimental group. Water-treated group was used as a negative control.

© J. Microbiol. Biotechnol.