JMB

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Table. 1.

Table. 1.

Metabiotics related with microorganisms and their neurological properties.

Components Microorganism Health functional properties References
Dopamine Lactobacillus reuteri ATG-F4 Increase of cytokine IL-10 and serum dopamine level (AD) [66]
Dopamine Lactobacillus plantarum PS128 Reduction of motor dyskinesia and neurol apoptosis (PD) [69]
Dopamine Bifidobacterium bifidum,
Bifidobacterium longum,
Lactobacillus rhamnosus,
Lactobacillus rhamnosus GG,
Lactococcus lactis subsp. lactis,
Lactobacillus plantarum LP28		 Protection of dopamine-releasing neurons
Decrease of motor dysfunctions		 [71]
GABA Lactobacillus sp.,
Bifidobacterium sp.		 Reduction of anxiety and depression (anxiety and depression) [53]
GABA Lactobacillus rhamnosus JB-1 Alleviation of anxiety and depression by decreasing corticosterone (anxiety and depression) [8]
GABA Lactobacillus rhamnosus YS9 Control nerve [57]
Histamine Lactobacillus sp.,
Lactococcus sp.,
Enterococcus sp.,
Streptococcus sp.,
Escherichia sp.		 Regulation of emotions Regulation of sleep and cognitive function (cognition) [53]
Metabolites Bacteroides fragilis NCTC 9343 Reduction of autistic behavior (AD) [49]
Metabolites Bifidobacterium breve A1 Reduction of neuroinflammation (AD) [67]
SCFA Lactobacillus rhamnosus,
Lactobacillus reuteri,
Bacterioides fragilis		 Regulation of anti-inflammatory pathways (AD) [53]
Serotonin Lactobacillus sp.
Lactococcus sp.,
Enterococcus sp.,
Streptococcus sp.,
Escherichia sp.		 Regulation of emotions, sleep, and cognitive function (anxiety and depression, cognition) [53]

GABA, gamma-amino butyric acid; SCFAs, short-chain fatty acids; AD, Alzheimer's disease; PD, Parkinson’s disease.
J. Microbiol. Biotechnol. 2024;34:487~494 https://doi.org/10.4014/jmb.2311.11023
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