Journal of Microbiology and Biotechnology

eISSN 1738-8872
pISSN 1017-7825

Table. 1.

Table. 1. Table 1

Cytotoxic effects of heat-killed cells of different LAB strains on cancer cell lines as assessed by the MTT assay.

Cell line	Cytotoxicity (%)
	LGG		KU22001		KU22002		KU22005
	8 Log CFU/ml	9 Log CFU/ml	8 Log CFU/ml	9 Log CFU/ml	8 Log CFU/ml	9 Log CFU/ml	8 Log CFU/ml	9 Log CFU/ml
AGS	0.98 ± 1.78^d	23.75 ± 2.15^b	2.08 ± 3.73^cd	23.92 ± 4.95^b	1.30 ± 1.79^d	26.09 ± 2.16^b	7.53 ± 2.34^c	32.15 ± 4.78^a
HT-29	3.01 ± 1.28^b	10.81 ± 2.05^a	2.04 ± 0.75^b	9.41 ± 0.96^a	1.58 ± 0.93^b	11.08 ± 1.57^a	1.56 ± 0.73^b	9.85 ± 1.32^a
DLD-1	17.97 ± 5.47^c	27.62 ± 1.67^b	28.63 ± 3.43^b	32.67 ± 5.26^b	34.08 ± 3.58^b	52.08 ± 3.42^a	34.90 ± 6.03^b	46.57 ± 4.82^a
LoVo	42.43 ± 5.37^b	46.86 ± 3.66^b	35.83 ± 2.11^c	56.18 ± 0.84^a	25.98 ± 2.45^d	54.37 ± 1.87^a	27.14 ± 3.20^d	59.40 ± 2.86^a
Caco-2	4.75 ± 0.92^e	17.43 ± 0.34^cd	23.07 ± 1.94^b	41.51 ± 4.89^a	20.32 ± 4.31^bc	38.15 ± 2.14^a	15.08 ± 1.87^d	39.73 ± 2.85^a
HeLa	2.68 ± 1.50^f	10.23 ± 1.49^d	17.64 ± 2.75^c	36.22 ± 1.50^a	12.35 ± 2.99^d	35.70 ± 1.12^a	6.41 ± 1.98^e	27.30 ± 2.73^b
MCF-7	3.60 ± 1.41^f	7.54 ± 0.93^e	24.03 ± 0.49^c	36.31 ± 1.70^a	19.05 ± 0.31^d	29.87 ± 1.62^b	19.08 ± 0.19^d	28.89 ± 2.64^b
A549	7.14 ± 0.78^e	15.19 ± 2.09^d	16.59 ± 1.25^d	26.24 ± 0.31^b	13.74 ± 2.18^d	23.61 ± 1.97^bc	21.13 ± 2.80^c	36.33 ± 0.90^a
HepG2	8.21 ± 1.27^e	28.35 ± 1.44^c	18.63 ± 1.25^d	41.92 ± 0.80^b	17.07 ± 0.86^d	40.59 ± 0.46^b	18.57 ± 0.29^d	44.00 ± 0.44^a

LGG, Lacticaseibacillus rhamnosus GG; KU22001, Enterococcus faecium KU22001; KU22002, Enterococcus faecium KU22002; KU22005, Enterococcus faecium KU22005.

The cell viability data are represented as the mean ± SD derived from three independent experiments.

Different letters above the value indicate significant differences for each characteristic (p < 0.05).

J. Microbiol. Biotechnol. 2024;34:902~910 https://doi.org/10.4014/jmb.2310.10050