Fig. 2. Analysis of differentially expressed genes and GO in LPS-stimulated macrophages.
(A) The volcano plot revealed 1216 upregulated genes (red) and 1787 downregulated genes (blue). Analysis of GO was focused on molecular functions, and it identified (B) GO terms associated with upregulated genes and (C) GO terms associated with downregulated genes. Both the volcano plot and GO analysis were conducted using a threshold of |log2 fold change| >= 1 and FDR < 0.05.