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Table. 2.

Table. 2.

Effect of Lactiplantibacillus plantarum DSR330 on relative gene expression associated with adipocyte differentiation and fat synthesis in HFD-fed mice.

Variable ND HFD Silymarin DSR-8 DSR-9
PPARγ 1.07 ± 0.06bc 1.55 ± 0.33c 0.31 ± 0.05a 1.42 ± 0.19c 0.80 ± 0.08ab
SREBP-1c 1.70 ± 0.14a 12.29 ± 0.48c 4.49 ± 0.75b 12.35 ± 0.90c 4.39 ± 0.49b
ACC1 1.15 ± 0.08c 0.18 ± 0.06a 0.59 ± 0.17b 0.93 ± 0.13bc 0.66 ± 0.09b
FAS 1.09 ± 0.01ab 4.86 ± 0.37d 0.94 ± 0.33ab 1.56 ± 0.20c 0.66 ± 0.01a

ND, normal diet (10% kcal fat); HFD, high-fat diet (60% kcal fat); Silymarin, HFD with silymarin; DSR-8, HFD with 108 CFU/day of DSR330; DSR-9, HFD with 109 CFU/day of DSR330.

Values represent the mean ± standard error.

Values with different letters indicate significant differences calculated at p < 0.05 according to Duncan's multiple-range test.

J. Microbiol. Biotechnol. 2024;34:399~406 https://doi.org/10.4014/jmb.2310.10026
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