Fig. 5. SGBP and RGX365 promote muscle regeneration by improvement in MyHC mRNA expression.
Changes in mRNA levels in four different isomers of MyHC in the TA muscle of SGBP-treated mice. The MyHC isomers include (A) MyHC 1, (B) MyHC 2A, (C) MyHC 2X, and (D) MyHC 2B (n=10). (E) Protein expression levels of MyHC isomers were evaluated with western blot analysis. Data are presented as the mean ± standard deviation (SD); *p < 0.05, **p < 0.01, ***p < 0.001 and ***p < 0.0001 (t-test, all experiments were biologically independent). Statistically non-significant results are not indicated in the figure.