Fig. 3.

Fig. 3. SGBP and RGX365 facilitate myogenesis and suppress muscle degradation mechanisms. Immunohistology of muscle cross-sections was used to confirm muscle regeneration in TA muscle tissue. (A) Immunohistochemistry analyses of laminin, embryonic MyHC, and MyoD for detection of myogenesis (scale: 75 μm). (B, C) Analysis of relative mRNA expression of factors related to muscle degradation (atrogin-1, MuRF1) and (D, E) muscle myogenesis (MyoG, MyoD) (n = 10).) (F) Western blot data related myogenesis and muscle degradation influenced by SGBP and RGX365. Data are presented as the mean ± standard deviation (SD); *p < 0.05, **p < 0.01, ***p < 0.001 and ***p < 0.0001 (t-test, all experiments were biologically independent). Statistically non-significant results are not indicated in the figure.

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