Fig. 2.

Fig. 2. Effect of SGBP and RGX365 on muscle atrophy in aged mice. Two-month-old and twenty-three-month-old male C57BL/6 mice were administered SGBP (25 mg/ml and 50 mg/ml) and RGX365 (5 mg/ml) for 30 days. (A) Grip strength. (n=10). (B) Immunohistochemistry analyses of MyHC, laminin, and H&E Staining for detection of muscle fiber morphology (scale: 100 μm, 75 μm). (C) The mean cross-sectional area (CSA) of each muscle fiber (n = 10). (D) Total muscle weight per body weight (n = 10). (E) Body weight of mice at day 30. Data are presented as the mean ± standard deviation (SD); *p < 0.05, **p < 0.01, ***p < 0.001 and ***p < 0.0001 (t-test, all experiments were biologically independent). Statistically non-significant results are not indicated in the figure.

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