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Fig. 7.

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Fig. 7. Effect of HLT-101 on the expression of Nrf-2 and inflammatory proteins in BPH-1 cells. (A) Fluorescence microscopic images of intracellular ROS by DCFDA assay. (B) Fluorescence microscopic images of NF-κB, (C) iNOS, and (D) Cox-2. (E) Western blot showing expression of NF-κB and Nrf-2/HO-1 in BPH-1 cells. Quantitative histogram of protein bands for the expression of (F) NF-κB, (G) Nrf-2, (H) HO-1, (I) iNOS and (J) Cox-2 in BPH-1 cells. BPH-1 cells were incubated for 6 h in culture medium containing TNF-α (10 ng/ml), INF-γ (10 ng/ml) and HLT-101 (5, 10, or 20) μg/ml. Data are expressed as the means ± SEMs (n = 8 per group). ####p < 0.0001, compared with the Con group, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared with the BPH group.
J. Microbiol. Biotechnol. 2024;34:1059~1072
© J. Microbiol. Biotechnol.