Fig. 5. Effect of the LMWCP on anagen induction in 7-week-old female C57BL/6 mice.
(A) Timetable of experimental treatments and sample collection. (B) Representative photographs of mouse back skin on days 0, 10, and 13. (C) Representative images of H&E-stained longitudinal and transverse sections of the skin of each mouse on day 13. Scale bar, 200 μm. (D) Skin color scores for 10 days. (E) Hair growth area on the back skin observed for 13 days. (F) Hair dermis thickness, (G) HF number, and (H) anagen/telogen ratios on day 13. (I) The expression levels of Wnt3a, β-catenin, PCNA, cyclin D1, and VEGF on the dorsal skin at day 13. The results are expressed as the mean ± standard deviation. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001 compared to the control group.