Fig. 6.

Fig. 6. Effect of amygdalin on oxidative stress induced on macrophages by the drug-resistant E. coli isolate. The real-time expression of SOD1, Nrf2 and HO-1 mRNA was detected by RT-PCR, as shown in (A). Detection of the target of amygdalin and Nrf2 by Macromolecular docking. (B) Representative results of the SOD1, Nrf2 and HO-1 protein expression analyzed by Western immunoblotting (C-E). The findings were validated using the Nrf-2 inhibitor ML385 (F-H). ^#P < 0.05 vs. the control group; *P < 0.05 vs. the drug-resistant E. coli-infected group; and ^&P < 0.05 vs. the KU group.

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