Fig. 4. Effect of amygdalin on the induction of PANoptosis by drug-resistant E. coli-infected cells.
The mRNA expression of caspase-3, caspase-7, and caspase-8 and the GSDMD and NLRP3 scorch genes was assessed by RT-PCR (A, B). The protein expression of necroptotic apoptotic proteins p-MLKL, p-PIPK3, and IGF2BP1 among all groups was analyzed by Western blot, and a statistical result was calculated (C, D). #P < 0.05 vs. the control group; *P < 0.05 vs. the drug-resistant E. coliinfected group.