Fig. 1.

Fig. 1. Scheme of pathway engineering for CHR and ANT production in Corynebacterium glutamicum. Red crosses indicate disrupted genes and bold blue arrows indicate enhanced steps through target gene overexpression. G6P; glucose-6-phosphate, F6P; fructose-6-phosphate, G3P; glyceraldehyde-3-phosphate, PEP; phosphoenolpyruvate, PYR; pyruvate, ACoA; acetyl-CoA, X5P; xylulose-5-phosphate, R5P; ribose-5-phosphate, S7P; sedoheptulose-7-phosphate, E4P; erythrose-4-phosphate, F6P; fructose-6-phosphate, DAHP; 3-deoxy-D-arabisoheptulosanate-7-phosphate, DHQ; 3- dehydroquinate, DHS; 3-dehydroshikimate, SHK; shikimate, S3P; shikimate-3-phosphate.

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