Fig. 1.

Fig. 1. Comparison of the mycelial morphology and tylosin production in shake flasks and 24-well plates. A: Mycelia in shake flasks and 24-well plates were sampled every 24 h were observed by microscopy. B: Dynamic monitoring of the yields of tylosin A as measured by HPLC obtained with shake flasks or 24-well plates culture. C: Dynamic monitoring of tylosin yields after growth in shake flasks or 24-well plates as measured by UV spectrophotometry (absorbance 290 nm). Data are shown as mean ± SD from three independent replicates in B and C.

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