Fig. 4.

Fig. 4. LINC01232 was negatively correlated with miR-181a-5p. (A). The binding site of LINC01232 and miR-181a- 5p was predicted by LncBase Predicted v.2. (B-C). The relationship of LINC01232 and miR-181a-5p was verified by dualluciferase reporter gene assay. (D-E). The expression of miR-181a-5p in SW-620 and LOVO cells transfected or untransfected with siLINC01232 and LINC01232 overexpression plasmid was determined by qRT-PCR. U6 served as an internal reference. ^#vs. Control, *vs. siNC, ^vs. NC; ^***or ^###or ^^^ p < 0.001. COAD, colon adenocarcinoma; qRT-PCR, quantitative reverse transcription polymerase chain reaction.

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