Fig. 3.

Fig. 3. LINC01232 overexpression enhanced cell invasion and expressions of c-myc, Bcl-2, and cyclin D1, and inhibited p53 and p16 expressions. (A-D). Transwell assay was conducted to test the invasion of SW-620 and LOVO cells transfected or untransfected with siLINC01232 and LINC01232 overexpression plasmid. (E-F). The expressions of p53, p16, c-myc, Bcl-2 and cyclin D1 were detected by qRT-PCR. β-Actin served as an internal reference. *vs. siNC, ^vs. NC; *or ^ p < 0.05, **or ^^ p < 0.01, ***or^^^ p < 0.001. c-myc, cellular-myelocytomatos; Bcl-2, B-cell lymphoma-2; p53, protein 53; p16, multiple tumor suppressor 1; qRT-PCR, quantitative reverse transcription polymerase chain reaction.

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