JMB

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Table. 1.

Table. 1.

Studies showing positive effect of protein supplementation on sarcopenia.

Protein Subject Amount Total protein intake Duration Exercise Results Ref.
Milk protein Physically active older adults (67-73 years) who were training on a 4-day walking event of 30, 40, 50 km/day with low habitual protein intake (<1.0 g/kg/day) 31 g 1.29 ± 0.28 g/kg/day 12 weeks - Lean body mass ↑
Fat mass ↓
[15]
Whey protein Prefrail and frail malnourished elderly aged 70-85 years (0.8 g/kg/day) 9.3 g whey protein, 0.5g fat, 0.2g cocoa powder 1.5 g/kg/day (1.2 g/kg/day: no significance) 12 weeks - Appendicular skeletal muscle mass, skeletal muscle mass index, gait speed ↑ [19]
Whey protein isolate (WPI) Healthy older men (mean age 67 ±1) 25 g WPI (including~3g leucine) twice directly after breakfast and lunch 1.5 g/kg/day (breakfast 0.45, lunch 0.55, dinner 0.5 g/kg/day) 12 weeks Resistance exercise (RE) twice /week WPI alone: gait speed ↑
RE alone: muscle strength, fat free mass, physical function ↑
No synergistic effects WPI and RE
[16]
Milk protein Mobility-limited older men and women (85±6 years) 34 g of milk protein (17 g protein x 2 times, morning, evening) 1.22 g/kg/day 10 weeks Heavy-load strength training, three times a week Leg lean mass, thickness, knee extensor strength, functional performance ↑ [20]
Milk protein Physically active older men and women (≥65 years) Total 36.8 g milk protein concentrate daily with 31 g protein, 1.1 g fat, 14.5 g lactose, consumed one during breakfast and one within 30 min after exercise 1.35 g/kg/day (Daily protein intake 0.92±0.27 g/kg/day) 12 weeks Trained for 4 day walking event of 30, 40, 50 km/day Lean body mass ↑
Fat mass ↓
[15]
Milk protein concentrate Elderly >60 years Milk protein drink (7.0 g of carbohydrate, 10.1 g of protein and 0.2 g of fat) 1.48 g/kg/day (Daily dietary protein intake is 1.2-1.3 g/kg/day) 6 months Daily exercise training (low-tomoderate intensity) Muscle mass ↑ [21]
Soy protein isolate (SPI) vs. whey protein isolate (WPI) Elderly aged 71±5 years WPI 20, 40 g SPI 20, 40 g WPI, SPI 20 g: 1.28 g/kg/day, WPI 40 g: 1.52 g/kg/day, SPI 40 g: 1.55 g/kg/day (Daily protein intake 1.0 g/kg/day) 1 day Rest or exercise Unilateral kneeextensor resistance exercise Rest+WPI 20 g, 40 g, exercise+WPI 20 g, 40 g, exercise+SPI 40 g: myofibrillar protein fractional synthetic rate ↑
40 g SPI was less effective than 20 g WPI
[17]
J. Microbiol. Biotechnol. 2023;33:143~150 https://doi.org/10.4014/jmb.2210.10014
© J. Microbiol. Biotechnol.