Fig. 2. Effects of SFEN on the production of pro-inflammatory cytokines in HaCaT cells.
The secretion levels of (A) IL-6, and (B) IL-8 were detected by ELISA. The expression levels of (C) IL-6 mRNA, and (D) IL-8 mRNA were detected using qPCR described in Materials and Methods. Bars marked with different letters (a–c) are significantly different (p < 0.05) according to Tukey's test. The hashes (#) indicate a significant difference (p < 0.05) compared to untreated control.