Fig. 4. Metabolic pathway of ethylene glycol to glyoxylate and other energy compounds.
This consists of PQQ (pyrroloquinoline quinone), which is reduced to PQQH2 upon conversion of ethylene glycol to glycolaldehyde and other compounds synthesized from glycolate. The enzymes shown are PedE/PedH, PQQ-dependent alcolhol dehydrogenase, Pedl, peroxisomal 3-ketoacyl-COA thiolase, GlcDEF, glycolate dehydrogenase, GlxR, tatronate semialdehyde reductase, Hyi,hydroxypyruvate isomerase and PykA/Pyk, pyruvate kinase.