Journal of Microbiology and Biotechnology

eISSN 1738-8872
pISSN 1017-7825

Table. 1. Table 1

Major cellular receptors for coronaviruses.

Cellular receptors	Tissue expression	Virus	Host	Reference for receptor
ACE2^a	Abundant in the epithelia of enterocytes of the small intestine	SARS-CoV	Human	[89]
	Widely expressed in a variety of tissues, including the lungs	SARS-CoV-2	Human	[43]
		HCoV-NL63	Human	[197]
DPP4^b	Widely expressed in the human body, including bronchial epithelial cells, alveolar type I and II cells, and activated lymphocytes	MERS-CoV	Human	[28]
9-O-Ac-Sia^c	Widely displayed on the surfaces of diverse cells and tissues, including the lungs, trachea, intestines, and colon	HCoV-OC43	Human	[5]
		HCoV-HKU1	Human	[4]
APN^d	Abundant in the epithelia of the kidney, small intestine, and liver Widely expressed in various tissues, including secretory bronchial epithelia	HCoV-229E	Human	[198]
		FCoV	Feline	[199]
		CCoV	Canine	[199]
		TGEV	Porcine	[26]
		PRCV	Porcine	[25]
CEACAM^e	Widely expressed in diverse human tissues, including the liver, small intestine, and colon, but not in lungs, bronchi, ovaries, or testes	MHV	Murine	[200]

^aAngiotensin-converting enzyme 2

^bDipeptidyl peptidase 4, also known as CD26

^c9-O-acetylated sialic acid

^dAminopeptidase N

^eCarcinoembryonic antigen-related cell adhesion molecules

J. Microbiol. Biotechnol. 2022;32:1073~1085 https://doi.org/10.4014/jmb.2206.06064