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Fig. 5.

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Fig. 5. TET3 was the target gene of miR-629-5p. (A) A Venn diagram was drawn to sort the candidate gene for miR-629-5p. (B-C) Relative mRNA expression of ZIC2, SIPA1L2, NR1D2, TC2N, NEDD4L and TET3 after upregulating or downregulating miR-629-5p in MG63 and SOSP-9607 was detected by qRT-PCR. (D) Predicted binding sites of TET3 and miR-629-5p from TargetScan V7.2 ( (E-F) Dual-luciferase reporter assay confirmed that TET3 was the target gene of miR-629-5p. All data were expressed as mean ± standard deviation (SD), which was indicative of three independent tests. #p < 0.05, ###p < 0.001, vs. inhibitor NC; *p < 0.05, ***p < 0.001, vs. mimic NC. TET3: tet methylcytosine dioxygenase 3.
J. Microbiol. Biotechnol. 2021;31:1331~1342
© J. Microbiol. Biotechnol.