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Fig. 7.

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Fig. 7. E2F7 was a target gene of miR-3127-5p. (A) The miRWalk (, miRDB (, starBase, Targetscan ( were used to predict miR-3127- 5p target genes. The Cancer Genome Atlas (TCGA) database ( analyzed mRNAs that are abnormal expressed in rectal adenocarcinoma. Venn diagram was used to analyze the intersection of the data generated from the databases. (B-C) SHBG and E2F7 expressions were detected by RT-qPCR. (D-F) E2F7 bound to miR-3127-5p as predicted and verified by Targetscan and dual luciferase assay. ++p < 0.01, +++p < 0.001 vs MC.
J. Microbiol. Biotechnol. 2021;31:1098~1108
© J. Microbiol. Biotechnol.