Fig. 2. LINC00174 modulated the viability and proliferation of colorectal cancer (CRC) cells.
(A) The expression of LINC00174 in human normal colon cell line and CRC cell line was detected by RT-qPCR. (B-C) The transfection rate of SW480 or LOVO cells transfected with LINC00174 overexpression or shLINC00174 was detected by RT-qPCR. (D-E) High expression of LINC00174 promoted cell viability; low expression of LINC00174 had done the opposite, as determined by Cell Counting Kit (CCK)-8. (F-I) Clone formation assay was used to test the effect of LINC00174 overexpression or knockdown on SW480 or LOVO cell proliferation. ++p < 0.01, +++p < 0.001 vs CCD-18Co; *p < 0.05, **p < 0.01, ***p < 0.001 vs Negative Control (NC).