Fig. 4.

Fig. 4. Cytotoxic mitochondrial targeting domain homologs induce endoplasmic reticulum (ER) disruption but not of peroxisomes. To observe ER and peroxisomes, HeLa cells were transfected with pEF.MYC.ER-E2-Crimson and pmTurquoise2-Peroxi. After treatment with R8:M-SDAD1 (5 μM, A), R8:M-TRRAD (20 μM, B), and R8:M-ST3GAL3 (40 μM, C), HeLa cells were observed using confocal and differential interference contrast microscopy with 405 nm and 594 nm laser.

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