Fig. 4.

Fig. 4. Inhibited miR-217 expression reversed the inhibitory effect of circ_0000144 silencing on GC cell proliferation. (A, B) The relative expressions of circ_0000144 and miR-217 were detected using qRT-PCR assay after transfection of si-circ_0000144, inhibitor or si-circ_0000144+ inhibitor in AGS and NCI-N87 cells. (C) The effects of circ_0000144 and miR-217 on cell proliferation were detected using colony formation analysis after transfection of sicirc_ 0000144, inhibitor or si-circ_0000144+ inhibitor in AGS and NCI-N87 cells. The experiment was independently conducted three times. ***p < 0.001 vs. siNC; ^###p < 0.001 vs. Si-circ_0000144; ^^p < 0.01, ^^^p < 0.001 vs. I. GC: gastric cancer; NC, negative control; I: miR-217 inhibitor.

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