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Fig. 4.

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Fig. 4. Epalrestat-reinforced ability of mitochondrion membrane by Rhodamine-123 staining. Graphical representation clearly displays the preventive effect of Epalrestat (50 μM) against H2O2 oxidative stress-induced mitochondrion membrane damage in RA-differentiated SH-SY5Y cells. H2O2 (100 μM) damaged the mitochondrial membrane more than 60% compared with control cells. In contrast, Epalrestat (50 μM) pre-treatment has protected significant level of MMP in H2O2- treated SH-SY5Y cells. The data are given as mean ± SD in each group. *p < 0.05 compared to control, #p < 0.05 compared to H2O2-treated group.
J. Microbiol. Biotechnol. 2021;31:867~874
© J. Microbiol. Biotechnol.