Fig. 1.

Fig. 1. Effect of prebiotics on DNCB-induced AD-like symptoms in NC/Nga mice. (A) Experimental design (B) DNCB-induced AD-like skin lesions and spleen size. (C) Spleen size-to-body weight ratio was evaluated. (D) The dermatitis score of AD-like skin lesions was measured to evaluate itch, erythema/hemorrhage, scaling/dryness, edema, and excoriation/ erosion. C: Control, N: Negative control (DNCB-induced), P: Zyrtec positive control (DNCB-induced + Zyrtec), T1: scGOS/ lcFOS (DNCB-induced + scGOS/lcFOS), T2: Inulin (DNCB-induced + Inulin), T3: β-glucan (DNCB-induced + β-glucan); *p < 0.05 versus control group; **p < 0.01 versus control group; #p < 0.05 versus negative control group; ##p < 0.01 versus negative control group. Data represent means ± SD of 5 replicates.

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