Fig. 4.

Fig. 4. Inhibitory effects of periplanetasin-5 on the gene expression and production of pro-inflammatory cytokines in LPS-stimulated Raw264.7 cells. (A) The level of IL-6 mRNA was determined through quantitative real- time PCR (left) and the IL-6 production levels in the culture media were measured by ELISA (right). (B) The levels of TNF-α mRNA were determined through quantitative real-time PCR (left) and the TNF-α production levels in the culture media were measured by ELISA (right). Data shown are means ± SD of triplicate experiments. #p < 0.05 compared to the control group. ***p < 0.001, **p < 0.01, *p < 0.05 compared to the LPS group. CTR, control; LPS, lipopolysaccharide.

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