JMB

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Table. 3.

Table. 3.

Potential anticancer effect of gut microbiota on human.

Probiotic strain Patients Reported effect Ref.
Enterococcus faecalis T110 Clostridium butyricum TO-A Bacillus mesentericus TO-A 75 patients: probiotic 81 patients: placebo 3-15 days before and the same day after CRC resection operation Superficial incisional surgical site infections (SSIs) ↓ Immune responses ↑ Intestinal microbial environment ↑ [67]
Pediococcuspentosaceus 5-33:3 Leuconostocmesenteroides 32-77:1 Lactobacillus paracasei ssp. paracasei 19 Lactobacillus plantarum 2362 38 patients: probiotic 37 patients: placebo The intervention period lasted 15 days before surgery GIQLI “Global score” ↑ Postcolectomy gastrointestinal function ↑ [68]
Saccharomyces boulardii 15 patients: probiotic 18 patients: conventional treatment 7 days before surgery and was interrupted on the operation day Mucosal IL-1β, IL-10, and IL-23A mRNA levels ↓ Both pro-and anti-inflammatory cytokines ↓ [69]
Bifidobacterium lactis Bl-04 Lactobacillus acidophilus NCFM 8 patients: probiotic 7 patients: placebo two daily tablets before surgery Microbial diversity ↑ Butyrate-producing bacteria ↑ CRC-associated genera ↓ [70]
Lactobacillus acidophilus NCFM Lactobacillus rhamnosus HN001 Lactobacillus paracasei LPC-37 Bifidobacterium lactis HN019 49 patients: probiotic 42 patients: placebo 5 days before and 14 days after surgery Postoperative infection rates ↓ [71]
J. Microbiol. Biotechnol. 2020;30:1607~1613 https://doi.org/10.4014/jmb.2002.02032
© J. Microbiol. Biotechnol.