Fig. 3. Lactate dehydrogenase (LDH) assay showed the cytotoxicity of the propolis extract and its fractions against LoVo, MDA-MB-231, HepG2, and MCF7 cells. The result revealed significant cytotoxicity at concentrations of 2xLC50. The data represent the means of three independent experiments. *p < 0.05 compared with the control group.