Fig. 1.

Fig. 1. Role of probiotics relevant to intestinal diseases via recovery of dysbiosis in the intestinal microbiota. Various intestinal diseases such as AAD, IBD, CD, and CRC are known to be closely associated with dysbiosis of the intestinal microbiota between host-beneficial and host-harmful intestinal bacteria. Once this balanced composition of intestinal microbiota is disrupted, it can cause diarrhea, inflammation, and even colon cancer. Administration of probiotics has been suggested as a therapeutic approach to prevent these intestinal diseases. Probiotics are recognized to have antimicrobial, anti-inflammatory, and even anti-carcinogenic activities, so they may assist in recovering the unbalanced intestinal microbiota. This recovery can also reduce these intestinal diseases or alleviate their symptoms. On the basis of this information, it is now widely believed that there is a strong connection between intestinal microbiota, probiotics, and intestinal health and disease.

© J. Microbiol. Biotechnol.