Fig. 1.

Fig. 1. Nattokinase enhanced survival of HCC-bearing mice. (A) Fibrinolytic activity of NCE with different molecular weight components from the culture supernatants of B. subtilis (n = 5, *** p <0.001). (B) Survival of HCC-bearing mice on each day (**p <0.01). (C) Ascites levels of HCC-bearing mice on each day (n = 8, **p <0.01). (D). Average appetite of HCC-bearing mice on each day (n = 8, **p <0.01). <10 K, 10~30 K, and >30 K: fractions of NCE with different molecular weights. (E) SDS-PAGE analysis of 10~30 K fractions of NCE from Bacillus subtilis natto inoculated fermentation medium at 6, 8, 12, and 24 h.

© J. Microbiol. Biotechnol.