Fig. 5. Inhibitory effect of heat-killed LAB strains on the MAPKs activation in LPS-induced RAW 264.7 cells. Cells were treated with heat-killed LGG or JW15 and stimulated with LPS for 30 min. Protein expression levels of MAPKs were determined with (A) Immunoblots and (B-D) relative quantification of band intensity. The results were expressed as mean ± S.D. of three independent experiments. *p < 0.05, compared to LPS positive group; #p < 0.05, comparison between LGG and JW15.