Fig. 3.

Fig. 3. Effect of silibinin on the spheroid formation of DP cells. (A) Human DP (HDP) cells were grown in a 3D-cultured system, and then treated with the indicated concentrations of silibinin (0 or 10 μM) for 24 h, and phase-contrast images of spheroids captured. (B) The spheroid diameter was quantified and graphed. The data are presented as the mean ± S.D. of three independent experiments. Values of p < 0.05 were considered statistically significant. 3D SC, three-dimensional spheroid cultured.

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