Fig. 1.

Fig. 1. Effect of silibinin on the viability of DP cells. (A) Chemical structure of silibinin. (B) Monolayered (2D)- and 3D-cultured DP cells were treated with different concentrations of silibinin (1– 200 μM) for 24 h and cell viability was determined using the WST-1 assay. The results are expressed as percent viable cells relative to the control. The data are presented as the mean ± S.D. of three independent experiments. Values marked by an * and ^#were considered statistically significant with p < 0.05. 2D, two-dimensional; 3D, three-dimensional.

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