Fig. 6.
Interaction of Lactobacillus rhamnosus GG (LGG) subjected to acid stress conditions with epithelial cells in the mucosa. Upon exposure to an acidic environment, pili genes of LGG such as spaF and spaC were highly expressed and the cells bound strongly to the gastrointestinal mucus layer of the host. These results indicated that the adhesion ability of LGG was enhanced after exposure to acid stress conditions.