Fig. 1.

Fig. 1. (A) Heat map showing the differentially expressed genes in Lactobacillus rhamnosus GG (LGG) exposed to acid stress at pH 4.5 for 1 h or 24 h. Under acid stress condition, 128 genes were significantly upregulated and 100 genes were significantly downregulated. Results were expressed as log2 (fold change of acid stress LGG/fold change of control LGG). Red or blue blots indicated genes that were detected as differentially expressed with p < 0.05. Differentially expressed genes: (B) upregulated and (C) downregulated genes in acid-stressed LGG were categorized based on biological process using the Cluster of Orthologous Groups of Proteins (COG) database.

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