Fig. 3.
The in vivo antiangiogenic activities of octaminomycins A (1) and B (2). Fertilized chick eggs were maintained in a humidified incubator at 37°C. At embryonic day 4.5, coverslips loaded with vehicle alone, 1 or 2 were placed to the CAM surface. Two days later, the chorioallantois was observed under a microscope. Calculations were based on the ratio of inhibited eggs relative to the total number of live eggs.