Fig. 4.
Inhibitory effect of conessine on dexamethasone-induced C2C12 myotube atrophy. (A) Representative photographs of C2C12 myotubes. The white bar represents the region of the C2C12 myotube used for diameter measurement. Black bars = 20 μm. (B) The diameter of the myotubes was measured using a high-power field with Image J. One hundred cells were measured and the graph shows diameters from 10% to 90%. Dexamethasone treatment vs. dexamethasone and conessine treatment, *p < 0.0001. (C) Schematic illustration of how conessine inhibits muscle atrophy.