Journal of Microbiology and Biotechnology
The Korean Society for Microbiology and Biotechnology publishes the Journal of Microbiology and Biotechnology.
Journal of Microbiology and Biotechnology
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2007 ; 17(8): 1227~1235

AuthorKim, Jong-Eun, Ji Yeon Kim, Ki Won Lee, Hyong Joo Lee
TitleCancer Chemopreventive Effects of Lactic Acid Bacteria
PublicationInfo J. Microbiol. Biotechnol.2007 ; 17(8): 1227~1235
AbstractLactic acid bacteria (LAB) provide several potential health and nutritional benefits, including improving the nutritional value of food, controlling serum cholesterol levels, and controlling some types of cancer. Numerous in vitro, in vivo, human, and epidemiological studies have provided evidence of the chemopreventive effects of LAB on colon, bladder, liver, breast, and gastric cancers. These effects act via diverse mechanisms, including alteration of the gastrointestinal micro flora, enhancement of the host's immune response, and antioxidative and antiproliferative activities. This review discusses the recent progresses on the chemopreventive effects of LAB on specific cancer types and the underlying molecular mechanisms.
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Keywordschemoprevetion, Lactic acid bacteria, cancer
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