2017 ; 27(1):
|Author||Amparo Jiménez-Quero, Eric Pollet, Minjie Zhao, Eric Marchioni, Luc Averous, Vincent Phalip|
|Affiliation||BioTeam/ICPEES-ECPM, UMR CNRS 7515, Université de Strasbourg, 67087 Strasbourg, Cedex 2, France|
|Title||Fungal Fermentation of Lignocellulosic Biomass for Itaconic and Fumaric Acid Production|
J. Microbiol. Biotechnol.2017 ; 27(1):
|Abstract||The production of high-value chemicals from natural resources as an alternative for
petroleum-based products is currently expanding in parallel with biorefinery. The use of
lignocellulosic biomass as raw material is promising to achieve economic and environmental
sustainability. Filamentous fungi, particularly Aspergillus species, are already used industrially
to produce organic acid as well as many enzymes. The production of lignocellulose-degrading
enzymes opens the possibility for direct fungal fermentation towards organic acids such as
itaconic acid (IA) and fumaric acid (FA). These acids have wide-range applications and
potentially addressable markets as platform chemicals. However, current technologies for the
production of these compounds are mostly based on submerged fermentation. This work
showed the capacity of two Aspergillus species (A. terreus and A. oryzae) to yield both acids by
solid-state fermentation and simultaneous saccharification and fermentation. FA was optimally
produced at by A. oryzae in simultaneous saccharification and fermentation (0.54 mg/g wheat
bran). The yield of 0.11 mg IA/g biomass by A. oryzae is the highest reported in the literature
for simultaneous solid-state fermentation without sugar supplements.|
|Keywords||Lignocellulosic biomass, solid-state fermentation, submerged fermentation, Aspergillus oryzae|
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